5-amino-1-(4-methoxyphenyl)-4-pyrazolecarboxylic acid

5-amino-1-(4-methoxyphenyl)-4-pyrazolecarboxylic acid - Names and Identifiers

Name	5-AMINO-1-(4-METHOXYPHENYL)-1H-PYRAZOLE&
Synonyms	5-amino-1-(4-methoxyphenyl)-4-pyrazolecarboxylic acid 5-Amino-1-(4-methoxyphenyl)-1H-pyrazole-4-carboxylic acid 1H-Pyrazole-4-carboxylic acid, 5-amino-1-(4-methoxyphenyl)-
CAS	14678-95-6
InChI	InChI=1/C11H11N3O3/c1-17-8-4-2-7(3-5-8)14-10(12)9(6-13-14)11(15)16/h2-6H,12H2,1H3,(H,15,16)

5-amino-1-(4-methoxyphenyl)-4-pyrazolecarboxylic acid - Physico-chemical Properties

Molecular Formula	C11H11N3O3
Molar Mass	233.22
Density	1.41±0.1 g/cm3(Predicted)
Melting Point	180-185 °C (dec.) (lit.)
Boling Point	462.2±40.0 °C(Predicted)
Flash Point	233.4°C
Vapor Presure	2.42E-09mmHg at 25°C
pKa	4.50±0.10(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.646
Physical and Chemical Properties	WGK Germany:3

5-amino-1-(4-methoxyphenyl)-4-pyrazolecarboxylic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	43 - May cause sensitization by skin contact
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves.
WGK Germany	3

5-amino-1-(4-methoxyphenyl)-4-pyrazolecarboxylic acid - Introduction

5-AMINO-1-(4-METHOXYPHENYL)-1H-PYRAZOLE &, chemical formula C12H12N2O3.

Nature:
The compound is an organic compound with the appearance of a white or off-white crystalline solid. It has a certain solubility, soluble in some organic solvents such as ketones and methanol.

Use:
5-AMINO-1-(4-METHOXYPHENYL)-1H-PYRAZOLE & is commonly used in organic synthesis reactions, especially in the synthesis of pyrazolone compounds in the field of medicine. It can be used as an intermediate for the synthesis of various drugs, such as anti-cancer drugs, anti-diabetic drugs, etc.

Method:
The preparation of 5-AMINO-1-(4-METHOXYPHENYL)-1H-PYRAZOLE & can be achieved by a variety of methods. A common synthetic method is to react p-methoxyaniline with an acid chloride to give an intermediate, which is then reacted with pyrazol-4-one to give the target product.

Safety Information:
5-AMINO-1-(4-METHOXYPHENYL)-1H-PYRAZOLE & has better safety, but as an organic compound, it is still necessary to pay attention to safe operation. During use, follow laboratory practices, avoid contact with skin and eyes, and avoid inhaling dust or gas. At the same time, storage should avoid contact with oxidants and strong acids. If exposed or taken by mistake, seek medical attention immediately and carry information about the chemical.

Last Update：2024-04-09 21:11:58